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Genetic Testing in Westbury, NY: Using DNA Data to End the Guess-Adjust-Wait Cycle in Psychiatric Care
DNA-guided pharmacogenomic testing that helps clinicians choose antidepressants your body is actually built to respond to, so the first choice has real odds of working.

Turning Prescribing Into an Informed Decision Rather Than a Best Guess

Ask any psychiatrist how they decide which antidepressant to try first, and the honest answer involves pattern recognition more than certainty. Symptoms get weighed. Side effect profiles get compared. Family response history gets factored in when available. But once the prescription is written, everyone waits. Three or four weeks pass before there’s enough data to know whether the choice landed. If it didn’t, the cycle restarts. Patients who need help now often spend the better part of a year finding out which options were never going to work.
The starting point can be smarter. Pharmacogenomic testing shows how your specific DNA responds to psychiatric medications, meaning the first prescription can be shaped by biology instead of statistical odds. Our team at Anxiety & Depression Psychiatry offers genetic testing in Westbury, often paired with our ketamine therapy service in Westbury, with additional research context available through the U.S. National Library of Medicine MedlinePlus Genetics.
The Three Kinds of Information the Test Delivers
The sample collection itself is straightforward: a soft swab against the inside of your cheek, done either in our office or through a mail-in kit sent to your home. Once processed, results come back to us within roughly a week and cover interactions with about 130 psychiatric medications. What we look at falls into three clinical categories.
Target Gene Activity
Some people have genetic variants that affect how well certain medications can work. For example, if you have a variant in the serotonin transporter gene with low activity, SSRIs like Prozac, Lexapro, or Zoloft are unlikely to help much. These are typically the first medications doctors try for depression. Knowing this upfront means we can skip them entirely and start with something more likely to work.
Drug Metabolism
Your liver enzymes determine how quickly you break down medications. Fast metabolizers clear drugs so rapidly that standard doses never reach effective levels. Slow metabolizers accumulate drugs in their system, leading to side effects even at low doses. This explains why some patients feel terrible on medications that work beautifully for others. Genetic testing identifies your metabolizer status for different drug classes, allowing us to adjust doses appropriately or choose alternatives.
Folate Metabolism
Folic acid is essential for producing neurotransmitters like serotonin and norepinephrine. If you have an MTHFR gene variant (which is quite common), you may not process folic acid efficiently. This can undermine antidepressant effectiveness. The solution is simple: we can prescribe methylfolate, an active form that bypasses the slow step, to boost your antidepressant response.
Why We Test Up Front Rather Than After Failed Trials
Some practices treat genetic testing as a last resort, reaching for it only after multiple medications have already failed. That approach costs patients time they can’t get back.
The math on that decision is worth being blunt about. Depression is estimated to be roughly 40 percent genetic and 60 percent environmental. Each new medication trial takes at least three to four weeks to evaluate. Failed trials produce side effects, disrupt daily functioning, and, more quietly, wear down the belief that anything will eventually help. Every unsuccessful prescription is more than just a scheduling problem.
Starting with genetic data changes the shape of that early period. It doesn’t guarantee that the first medication will be the one, but it removes the medications your biology was never going to accommodate — which for a lot of patients is the difference between finding relief this quarter and finding it next year.
What Testing Isn't Designed to Do
Pharmacogenomic testing is a real clinical tool, but it isn’t a diagnostic oracle. It can’t tell us that a specific medication will work. What it can do is confirm that your genetics don’t create an obvious obstacle. It doesn’t replace clinical judgment, and it doesn’t stand in for a full psychiatric evaluation. The test is a layer, not the whole picture.
Skeptics still argue that the science hasn’t matured enough for routine use. That argument is losing ground. Medicare, Medicaid, and United Healthcare all reimburse pharmacogenomic testing, which is a strong regulatory signal that the evidence base has held up under scrutiny. A genetic testing clinic in Westbury, NY working within those coverage frameworks is operating in a fundamentally different landscape than the field did five years ago.
A Better Framework for the "Sensitive Patient"
Patients who react badly to several psychiatric medications used to be described as sensitive, difficult, or overly reactive. The language pathologized what turns out to be, in many cases, straightforward biology. If you’ve been unable to tolerate multiple medications at standard doses, there’s a good chance you carry a slow-metabolizer genotype that causes drugs to accumulate in your system.
Naming that dynamic isn’t cosmetic. Once we know how your body handles a given drug class, we can select medications and doses your physiology can actually tolerate, which usually changes the entire clinical trajectory.
Long Island Location
Anxiety & Depression Psychiatry
300 Old Country Rd, Suite 351 Mineola, NY 11501
(646) 830-0131help@tomerlevin.comOffice Hours: Monday to Friday: 8am – 5pm
Our Mineola location is convenient to Garden City, Westbury, and central Nassau County. We’re close to NYU Winthrop Medical Center and Northwell Health’s Long Island Jewish Medical Center and Zucker Hillside Hospital.
Frequently Asked Questions
How is the test done?
It’s just a painless swab of your inner cheek. We can do it in the office, or a kit can be mailed to your home so you don’t need an extra visit.
How long until results come back?
Typically about one week.
Is genetic testing covered by insurance?
Medicare, Medicaid, and United Healthcare cover pharmacogenomic testing. Coverage from other insurers varies, but many are beginning to cover it. We can help you check your specific plan.
Should I get tested if I'm already on a medication that works?
If your current medication is working well, testing may not be necessary. However, the information can still be valuable if you ever need to change medications or add new ones.
Does the test tell you exactly which medication to prescribe?
Not exactly. It identifies which medications are more or less likely to work based on your genetics. Your psychiatrist combines this information with clinical assessment to make the best recommendation.
Where the Right Starting Point Meets
Genetic testing in Westbury, NY can shift what your first treatment decision looks like. Call us at (646) 830-0131 to schedule a consultation and learn whether pharmacogenomic testing is right for you.
I feel that, although it is new, psychopharmacogenomic testing is a game changer for psychiatry. — Dr. Tomer Levin
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